Cannabis Effective in Easing Symptoms of Neuropathy: Relief without Troublesome Side Effects or Opioids

By Dan Reich

Neuropathy is one of the most common forms of chronic pain, and is caused by damage to the nervous system. Symptoms can include feelings of muscle weakness, numbness, tingling and burning. Affecting as many as 20 million Americans according to the National Institute of Health, it can be caused by disease (diabetes is the most common) but other autoimmune diseases such as multiple sclerosis, lupus, rheumatoid arthritis and thyroid disorders can also result in neuropathy. 

Other causes include alcoholism, exposure to toxins, chemotherapy, HIV, Fibromyalgia, Shingles, surgery, viral infections and injuries. With diabetic neuropathy, the nerve damage is caused by chronically high blood sugar. Sufferers of neuropathy numbness in the feet (the most common location) can injure their feet without being aware of it, and can suffer infections or other complications.

Free radicals, which are generated when the body encounters stress, toxins, poor lifestyle habits, can damage nerve endings, exaggerating the effects of the condition. Cannabis is rich in antioxidants, helping to diminish oxidative stress and irritation.

Conventional pain relieving drugs have traditionally had a hard time mitigating the pain of neuropathy, as they usually work by reducing inflammation, which is a common source of pain. Neuropathic pain is not caused by inflammation but rather nerve damage, and due to the way that cannabinoids bind with the body’s pain receptors, they can block the sensation of pain.

Another advantage provided by medical cannabis is that topicals, such as Synergy’s double-strength Super Salve, with its 1:1 THC for optimum pain relief, can quickly direct relief to the affected area, instead of waiting for it to be absorbed by the entire body as would be the case with edibles or tinctures.

Further, it doesn’t take a lot of medicine to be effective. Nurse practitioner Lynn Haslam says she typically starts neuropathic pain patients on a low nighttime dose of a balanced CBD to THC oil (1:1). “We really want the pain managed so they can sleep,” she says. “Neuropathic pain typically gets worse at night, electric shock-like. We may not be able to diminish all of these sensations, but if we can restore sleep, which will help decrease pain during the day, that may be a reasonable goal.” If the 1:1 ratio is too strong, then start with a 4:1 blend.

Cannabis Pharmacy author Michael Backes writes that this study is particularly significant because the best results were observed at the lowest dose, highlighting “the unexpected medical effectiveness of cannabis dosages that are far below those commonly consumed within the medical community.”

Author Michael Backes details in his book Cannabis Pharmacy a study finding a single, small, inhalation of THC cannabis decreased neuropathic pain at a higher rate than did larger doses ( 2mg). Significantly, this is a non-pscho-active dose that would allow for patients to treat their pain without any alteration of consciousness.

A number of studies have established the efficacy of cannabis in relieving neuropathy symptoms. A 500-person study by the National Institute of Health revealed that more than 85% of participants reported a decrease in the amount of neuropathic pain. Other studies have indicated that THC, or balanced combinations of THC and CBD, effectively relieves neuropathic pain. ( Synergy Wellness offers 4:1 CBD:THC blends, #116 4:1 Sativa for daytime relief, #103 4:1 Indica for pain relief at night). 

Certain strains, especially those high in CBD, have earned a reputation as being particularly effective, such as ACDC. Other popular strains for neuropathy include Granddaddy Purple, Sour Diesel and Blue Dream, which are high in THC for pain relief. Much like flower, vape cartridges provide a quick onset of relief. Synergy stocks high THC cartridges for rapid pain relief ; Blue Dream, Sour Diesel and the CBD-rich   ACDC.  If you want to avoid psychoactive effects, topicals and suppositories are extremely effective for providing pain relief without getting you high.

Whatever your preferred method of consuming cannabis, whether edibles, tinctures, topicals, capsules or flower, if you suffer from neuropathy there is probably a product that will provide the relief you are seeking. We are happy to consult with you to help you find the solution that will work best for you.

References:

Synergy Member Testimonial: A Journey with Pain Management over the years!

Hello, my name is Sarah Gould-Biggs.

I am 40 years old, and at 18, I was in a tragic accident. For many, many years afterwards, I had surgery after surgery, with dozens of medications.

To this day, I have chronic injuries and pain because of them, yet I try to lead an active life.

I began with the tinctures and did them for about one year. However, because of digestive issues and reflux, I was unable to continue, so I switched to the suppositories. They were quite relieving at first and worked well for pain for two years. Then, I felt my body build a tolerance to them, as with many other things. I stopped for four or five months, then my pain became unmanageable again.

I restarted them just a couple nights a week and felt relief. With the guidance of Leonard, I have started a new protocol, and will hopefully find daily relief again.

I cannot thank Synergy Wellness & Healing Essence, Leonard, and the rest of the team that has helped me the last few years.

All the praise, love, and light.

Sarah Gould-Biggs

July, 2023

Cannabinoids Galore!

Our cannabis knowledge is increasing exponentially thanks to scientific enquiry and we are constantly learning more about the potential health benefits of cannabinoids.

So far, over a hundred cannabinoids have been identified in the cannabis plant and research is underway to discover the attributes of many of these unique compounds. Current studies show particular interest in CBV, CBC and THCV.

Cannabinoids derived from cannabis are phytocannabinoids, meaning from plants, incredibly they match the endocannabinoids that exist in all mammals and play a central role in maintaining health.

Medical science now acknowledges that auto-immune conditions are linked to deficiencies in the endo-cannabinoid system (ECS) and that an emphasis on a healthy ECS brings wide-reaching health benefits. Well documented successful treatment of epilepsy, digestive disorders, arthritis, anxiety and depression and cancer are driving more research.

Currently it’s open season for scientific cannabinoid studies and new research is revealing other plants which contain significant phytocannabinoids.

We are living through a paradoxical moment in cannabinoid awareness: On the one hand, scientific research shows how cannabinoids support our ECS ( Endocannabinoid system) which functions to maintain balance in the body, on the other hand, cannabis, the main source of phytocannabinoids remains illegal in many countries. The legal issues of cannabis stem from the presence of THC, the only psychotropic cannabinoid that has been discovered.

This has led to the extraction of cannabinoids, most notably CBD, from industrial hemp, which contains less than 0.3% THC. Hemp doesn’t contain the same level of cannabinoids as cannabis so hemp-derived CBD means vast amounts of hemp are needed to meet demand.

Science has revealed that small amounts of cannabinoids occur in a wide range of plants; chocolate, black pepper and liverwort are just three examples. Though these sources are not viable for extraction, other plants are yielding some astonishing results.

A recent study by a team led by molecular biologist Rodrigo Moura Neto of the Federal University of Rio de Janeiro, has discovered that a common weed that grows all over Brazil contains large amounts of CBD, but no THC.

Trema Micrantha Blume is a prolific shrub, native to South America and growing wild all over the sub-continent. Neto’s research team found high levels of CBD in the plant and have been awarded a research grant from the Brazilian government to continue their work. Neto is excited about the possibility of a viable source of CBD which sidesteps the illegality of cannabis in Brazil.

The CBD market alone is a 5 billion dollar industry worldwide and is predicted to reach 47 billion dollars by 2028, fuelled by high demand from the health and wellness industry.

The discovery of CBD-rich Trema Micrantha Blume holds promise for the future, potentially providing medicine and an economic boost for South America. Who knows where we’ll find cannabinoids next?